What Is Agnogenic Myeloid Metaplasia?

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It happens when scar tissue grows in the bone marrow so that not enough blood cells are produced for the body.
According to the NIH (National Cancer Institute), Agnogenic myeloid metaplasia (aka. chronic idiopathic myelofibrosis, idiopathic myelofibrosis, myelosclerosis with myeloid metaplasia, and primary myelofibrosis) is a progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as the liver and the spleen, instead of in the bone marrow. This disease is characterized by an enlarged spleen and progressive anemia.
How about its symptoms?
Agnogenic myeloid metaplasia is a disease that usually develops slowly. In initial stages, many people don't experience any symptoms. As disruption of normal blood cell production increases, possible symptoms may include: Fever, bone pain, easy bruising or bleeding, excessive sweating during sleep (night sweats), feeling tired, weak or short of breath, usually because of anemia. In some cases, it also causes pain or fullness below your ribs on the left side, due to an enlarged spleen.
Been having this unexplained bone pain, fever and bleeding for a while. I never climb stairs because I can’t catch my breath. How do I know if I have agnogenic myeloid metaplasia? And any possible treatment?
Hi, you’ll need to make an appointment with a professional ASAP! The doctor will help you figure out the underlying causes of your condition.
First, get yourself a doctor! You need to identify if your symptoms are caused by this condition! To make a precise diagnosis, the doctor may order a series of tests and procedures. For example, you may need to undergo a physical exam, some blood tests, imaging tests, bone marrow examination and even gene tests if necessary. In order to determine which treatments are most likely to benefit you, your doctor may use one or more formulas to assess your condition. based on your current condition, the doctor may provide several options. There are treatments for anemia and treatments for an enlarged spleen. In some cases, one may also need a bone marrow transplant or palliative care. It all depends on the underlying cause and severity of your condition!
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