Do toxic chemicals cause brain problems?

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I am 50 and have a seizure problem.

2 Answers

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Hi, Linda.

The causes of seizure are as follows:          

  • Congenital factors: genetic factors, congenital hydrocephalus, congenital brain malformation, etc;             
  • Postnatal factors: brain injury, alcoholism, chemical poisoning (such as heavy metal, pesticide poisoning), cardiovascular and cerebrovascular diseases.

That would certainly be very possible. Seizurogenic chemicals include a variety of toxic agents, including chemical warfare agents, toxic industrial chemicals, and natural toxins. Chemical weapons such as sarin and VX, and pesticides such as parathion and carbaryl cause hyperstimulation of cholinergic receptors and an increase in excitatory neurotransmission. Glutamatergic hyperstimulation can occur after exposure to excitatory amino acid toxins such as the marine toxin domoic acid. Other pesticides such as lindane and strychnine do not affect excitatory neurotransmission directly, but rather, they block the inhibitory regulation of neurotransmission by antagonism of inhibitory GABA and glycine synapses. In this paper, chemicals that cause seizures by a variety of molecular mechanisms and pathways are discussed.