Complications of a bone marrow aspiration/biopsy.

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Bone marrow exams are generally safe procedures. Complications are rare but can include:

  • Excessive bleeding, particularly in people with low numbers of a certain type of blood cell (platelets)
  • Infection, especially in people with weakened immune systems
  • Long-lasting discomfort at the biopsy site
  • Penetration of the breastbone (sternum) during sternal aspirations, which can cause heart or lung problems
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