local, regional, distant meaning what ? I have metastasized endometrial and not really interested in doing chemo. I have had chemo treatments 2 x in past 10 years, one for lumpectomy, and 1 for endometrial in abdomen. This time it went to lymph node in armpit. Chemo damaged my heart and gave me neuropathy. Thinking about just trusting in God and riding out the storm.