do you have other symptome beside high BP? have you run other tests？how long this happened? you can add another drug seen if the BP gets better or not.if 3 kind of anti-BP drug is not working,IT'S called refractory hypertension . you should do some blood test for endocine system. chronic renal disease can bring to high BP. go to cardiologist to follow-up your BP. WISH YOU GET BETTER.