What Are Causes of Thrombocytopenia?

3 Answers

These messages are for mutual support and information sharing only. Always consult your doctor before trying anything you read here.
Was looking for a lifespan for someone with genetic TTP. Was diagnosed at 3 years old and I got Hepatitis C from my very first transfusion in 1977. I am now 44 and my body seems to be falling apart. I can't even keep my counts normal for 2 weeks. I wasn't sure I'd make it to 18 but I moved from San Diego to Denver and met a Doctor who saved my life.
With the clinical application of plasma exchange, the prognosis has been greatly improved, and the mortality rate has dropped to 10-20%. Studies have shown that ADAMTS13 activity in patients with TTP is an ideal prognostic indicator. The recurrence rate of TTP patients with severe ADAMTS13 deficiency was higher than that of non-severe patients, 60% and 19%, respectively.
 you may live a long time ,new methods of medication is on the way .someday you may get a gene-editing therapy. that's possible,maybe in years.
try to stay positive.
Thank you for this site. I am newly diagnosed with TTP. After much research, I am relieved that the dr caught it early , however, I have changed my life 360 degrees. I am 57 and feel positive for the future thanks to Pheresis Ribuxan treatments. A lot of them. Hang in there and POSITIVITY is key ❣️
my mother had an operation to have her spleen removed in the 1950's, i was born a year later , i already had an older sister,  they told my mother that her daughters could also  inherit this, I am not sure if this was what she had or not , my sister then  at about 30 had to have hers removed but i never did , will my   granddaughters be at risk for this also ? i am not 65,
sincerely \
Michelle R. Leighty
I am not sure what is the primary disease for spleen remove. I can't answer your question.
Which meds cause thrombocytopeia
Most antineoplastic drugs, sulfonamides and streptomycins in antibiotics, isoniazid and rifampicin in antituberculosis drugs, phenytoin sodium in antiepileptic drugs, analgesics and antipyretics, methyl dopa in antihypertensive drugs, thiazide in diuretics, acetylsalicylic acid in antiplatelet drugs, heparin in anticoagulants, and estrogen Drugs and so on. Patients may develop thrombocytopenia within hours to days after taking the above drugs. There are also anti-rheumatic analgesics such as Baotaisong and indomethacin, which are currently more common drugs leading to drug-induced thrombocytopenia. In addition, there is a powerful narcotic analgesic drug, morphine, which occasionally causes immune thrombocytopenia. Morphine-dependent anti-platelet antibodies can be found in the serum of patients. Morphine, as a powerful analgesic, is often used in severe pain and in patients with advanced tumors. It is necessary to observe the changes of platelets in order to find out the problems in time and treat them properly.
I hope the above information will be useful to you.
Thank you.  I was just in the ER and was told my platelets were very low I am 63 years old and never had this problem before.  Is it something that could just come and go?
Hi Vanessa
I’m certainly no expert on TTP but I can tell you I’m becoming one quickly!  In my experience, it came on in 4 days only. I didn’t have any of the “normal “ symptoms. I can tell you if your platelets go low , mine were 30, get to the ER .  There is help getting the platelets up rather quickly.
Best of luck ❣️