What’s to Know About Metastatic Bladder Cancer

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Bladder tumors are the most common malignant tumors in the urinary system, ranking 7th in male malignant tumors and 17th in females. Assessing lymphatic metastasis is not only important for the prognosis of patients with bladder cancer, but also important for the treatment of patients with bladder cancer. Accurate clinical staging of bladder cancer is the basis for formulating treatment plans and prognosis, and accurately assessing whether lymph nodes are metastasized or not. Especially the degree of transfer
The essential.
1 gene level
1.1 SPRY4-IT1 gene
1.2 PD41-08 gene profile
1.3 FXYD3 and KRT20 genes
1.4 Transcription factors FoxO3 and FoxO4
2 molecular level
2.1 vascular endothelial growth factor
2.2 transforming growth factor (transformation growth factor,
TGF) -β1 and Smad4 proteins
2.3 chemokine 5 (C-X-C motif ligand, CXCL5)
2.4 tyrosine kinase receptor AXL397
2.5 cell surface markers CD34 and podoplanin
2.6 Mammary Serine Protease Inhibitor
3 cell and tissue levels
3.1 monocyte ratio and neutrophil/lymphocyte ratio
3.2 microvascular or lymphatic vessel density
Biological evaluation methods have unique advantages as non-invasive, prospective evaluation methods, such as detection of VEGF expression in human peripheral blood and CXCL5 expression in urine at the molecular level, and detection of monocyte ratio and neutrophil at the cellular level. The cell/lymphocyte ratio is easy to obtain before the test, the repetitive operation is strong, and the clinical application is highly feasible. The current detection of SPRY4-IT1 gene, FXYD3 and KRT20 genes, transcription factors FoxO3 and FoxO4, detection of TGF-β1 and Smad4 protein, tyrosine kinase receptor AXL397, cell surface markers CD34, podoplanin, Maspin, and microvascular or The detection samples of lymphatic vessel density are postoperative resected bladder cancer tissues, which have hysteresis in time, and histological materials are relatively difficult. Therefore, the guiding significance of preoperative guidance is limited, but w
Yikes!...Now I need 4 years of advanced schooling to be able to translate the answer.
Thanks for all the info you liars, this is another thing wrong with society