It's over the normal limit, and it's called thrombocytosis.
1. Reactive thrombocytosis
Found in infection, postoperative surgery, malignant tumors, splenectomy, acute blood loss or iron deficiency, trauma, non-infectious inflammation, etc. These causes an increase in the release of platelet-promoting factors (such as thrombopoietin, interleukin-6). Causes thrombocytosis.
2. Spontaneous thrombocytosis
Found in myeloproliferative diseases, such as polycythemia vera and early myelofibrosis, chronic myeloid leukemia.
3. Primary thrombocytosis
The pathogenesis may be related to thrombopoietin and thrombopoietin receptor changes and downstream pathway activation. 50% of patients with essential thrombocytosis have JAK2V617F gene mutation, 3% to 5% of patients have MPL gene mutation, and 15% to 25% of patients have CALR gene mutation.
Platelet count ≥ 450 × 109 / L,can be diagnosed with Thrombocytopenia. have it test a month later.