i was in my early 30's when the doctors did the PSA test. then came the one where they take little chunks of the prostate. i can tell you the first 5-7 chunks they took , was no problem. the rest of them hurt more each time they took another chunk. fun huh. they took out the prostate, they used a garden hose for a catheter ill tell you, then they left it in a extra week. i also tried the shots directly into it. its not to painful, except when the phamacy deciededs to use a larger size needle., thats painfull, i trusted the pharamcy to give me the smallest needle, dont trust. now that was aprox. 30 years now. i leak like a siv. you can count on not having sex any longer besides what they tell you.