In 1 to 3 days, the skin of the affected area appears papules with large mung bean size and tension, and vesicles are distributed along the nerves, clustered and arranged in strips. The person suffering from this disease is mainly characterized by fatigue and weakness, loss of appetite, mild fever, and soon the affected area feels hot with pain or itching. Some cases can be painless, but itchy, or only erythema without obvious herpes; severe pain is obvious, sitting restless, after a few days from clear and transparent blisters into turbid pustules, some can be broken to form erosion. Older patients often experience severe pain, which affects sleep. If the treatment is not timely or inappropriate, the pain remains after the skin lesions subsided. The sequela of herpes zoster is repeated neuropathic pain. The main feature of postherpetic neuralgia is severe and intractable pain. After the recovery of herpes zoster lesions, the pain persists.