That is because the increase in serum iron absorption.
Hereditary hemochromatosis (HH), also called genetic hemochromatosis, is a genetically determined disorder in which mutations of certain genes involved in iron metabolism can cause increased intestinal iron absorption.
The clinical manifestations of this disorder (and of other forms of iron overload) are related to iron deposition in tissues, such as the liver, pancreas, and heart.
Excess iron is absorbed in a substantial organ, and dysfunction occurs.
Skin pigmentation, cirrhosis and diabetes are typical triads