Of cuz, it means atherosclerosis. it is a disease in which the inside of an artery narrows due to the build up of plaque.Initially, there are generally no symptoms. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which arteries are affected. Symptoms, if they occur, generally do not begin until middle age Atherosclerosis generally starts when a person is young and worsens with age.Almost all people are affected to some degree by the age of 65. Atherosclerosis is the number one cause of death and disability in the developed world.