Clinical Trial – Treating Constipation in MS – Constipation

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The investigators seek to test whether incorporating the scheduled dosing of a bisacodyl 10 mg rectal suppository every other day improves bowel-related symptoms in patients with multiple sclerosis. Patients will be randomized to receive either a placebo suppository or bisacodyl suppository dosed every other day for 4 weeks.
Study Type  : Interventional  (Clinical Trial)
Estimated Enrollment  : 70 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
Official Title: Treating Anorectal Dysfunction Associated With Multiple Sclerosis
Study Start Date  : June 2016
Estimated Primary Completion Date  : December 2019
Estimated Study Completion Date  : April 2020
Contacts David J Levinthal, MD, PhD            412-303-0525 Identifier: NCT02609607
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