Clinical Trials - The Effect of Naloxegol in Cancer Opioid-Induced Constipation - Constipation

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Opioid-induced constipation (OIC) is a common symptom in patients. Naloxegol has been proved to be helpful in relieving the pain caused by cancer. The purpose of this study is to compare the effect of naloxegol versus the patient's usual care in treating opioid-induced constipation, as well as the effect on the patient's quality of life and how much pain is experienced.
Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: A Phase II, Randomized, Single Center, Pilot Feasibility Study to Evaluate Naloxegol for Opioid-Induced Constipation in Cancer Patients
Study Start Date : May 2016
Estimated Primary Completion Date : April 2020
Estimated Study Completion Date : April 2021
Contact: Chelsea Hagmann Identifier: NCT02745353
For enrollment please visit