Clinical Trial - Metformin for Treating Autosomal Dominant Polycystic Kidney Disease - Polycystic Kidney Disease

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This study will test to see if metformin is safe and if it is effective compared to placebo in adult Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients with beginning stages of chronic kidney disease. We will also measure its effect on progression of kidney disease as reflected in the kidney size and the kidney function, along with its effect on kidney pain and quality of life.
Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 96 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease
Study Start Date : May 2016
Estimated Primary Completion Date : June 2020
Estimated Study Completion Date : September 2020
Contact: Linda Whiting, MBA 412.641.2568
Contact: Susan Spillane, RN 412.692.4848 Identifier: NCT02656017
For enrollment please visit