What Is Amyloidosis and What Causes It?

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Amyloidosis is a rare disease that occurs when an abnormal protein called amyloid builds up in your organs. The types of amyloidosis include
  • AL amyloidosis (immunoglobulin light chain amyloidosis)
  • AA amyloidosis
  • Hereditary amyloidosis (familial amyloidosis)
  • Dialysis-related amyloidosis
Causes Generally speaking, the buildup of an abnormal protein called amyloid leads to amyloidosis. The corresponding causes of above four types of amyloidosis are as follows:
  • bone marrow produces abnormal antibodies that can't be broken down
  • chronic infectious or inflammatory diseases
  • gene abnormalities
  • proteins in blood are deposited in joints and tendons