In general, asphyxiation and suffocation are very similar in meaning. They both refer to a condition caused by severe deficiency of oxygen supply to the body.
Asphyxiation or suffocation arises from constriction or obstruction of airways, such as asthma, laryngospasm, or simple blockage from the presence of foreign materials. And it also can be caused in an environment which cannot offer enough oxygen, such as underwater, in a low oxygen atmosphere, excessive smoke, or in a vacuum.
We can say there is no significant difference between asphyxiation and suffocation.
Keywords: asphyxiation vs suffocation