Can You Talk About Drugs for Depression?

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Depression is a condition that affects the brain, so drugs that work on the brain may be helpful in combating the mental issue. Here are some common medicines for depression:
  • Selective serotonin reuptake inhibitors (SSRIs). They can reduce serotonin reuptake in the brain, leaving more serotonin working in the brain. SSRIs include sertraline, fluoxetine, and citalopram.
  • Serotonin and norepinephrine reuptake inhibitors (SNRIs). These drugs can improve serotonin and norepinephrine levels in the brain, which helps relieve symptoms. SNRIs medicines include desvenlafaxine, levomilnacipran, and duloxetine.
  • Tricyclic antidepressants (TCAs). Your doctor prescribes TCAs when you don't respond to SSRIs or other antidepressants. These drugs include amoxapine, amitriptyline, and clomipramine.
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