What Are the Causes of Grand Mal Seizures?

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The main cause of grand mal seizures is that the electrical activity over the whole surface of the brain becomes abnormally synchronized. Besides, other factors may lead to grand mal seizures including:
  • Congenital or developmental abnormalities
  • Blood vessel malformations in the brain
  • Genetic syndromes
  • Brain tumors
  • Metabolic disturbances
  • Very low blood levels of glucose, sodium, calcium or magnesium
  • Withdrawal syndromes
  • Using or withdrawing from drugs, including alcohol
  • Injury or infection
  • Traumatic head injuries
  • Infections, such as encephalitis or meningitis, or a history of such infections
  • Injury due to a previous lack of oxygen
  • Stroke
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