Sep 6, 2019
A research team has found a compound that works to promote rebuilding of the protective sheath around nerve cells that is damaged in conditions such as multiple sclerosis.
Myelin forms a protective sheath covering each nerve cell. Damage to myelin is associated with MS, stroke, brain injuries, and certain forms of dementia such as Alzheimer's disease.
Researchers found that a molecule called hyaluronic acid, or HA, accumulates in the brains of patients with MS. HA then breaks down into small fragments in multiple sclerosis lesions by enzymes called hyaluronidases. Hyaluronidases leads to failure of generation of myelin.
Now researchers have found a modified flavonoid—a class of chemicals found in fruits and vegetables, that can block hyaluronidases and promote remyelination.
The team is preparing for clinical trial, in a year the result will come out if this will work for human being with MS.