Any Treatment for Relapsing Multiple Sclerosis?

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Treatment options for relapsing-remitting MS include:
  • Beta interferons. These medications are among the most commonly prescribed medications to treat MS.
  • Ocrelizumab (Ocrevus). This humanized immunoglobulin antibody medication is the only DMT approved by the FDA to treat both the relapse-remitting and primary progressive forms of MS.
  • Glatiramer acetate (Copaxone). This medication may help block your immune system's attack on myelin and must be injected beneath the skin.
  • Dimethyl fumarate (Tecfidera). This twice-daily oral medication can reduce relapses.
  • Fingolimod (Gilenya). This once-daily oral medication reduces relapse rate.
  • Teriflunomide (Aubagio). This once-daily medication can reduce relapse rate.
  • Natalizumab (Tysabri). It may be considered a first line treatment for some people with severe MS or as a second line treatment in others.
  • Alemtuzumab (Lemtrada). This drug helps reduce relapses of MS by targeting a protein on the surface of immune cells and depleting white blood cells.
  • Mitoxantrone. Mitoxantrone is usually used only to treat severe, advanced MS.
Key word: treatment relapsing multiple sclerosis
Sep 6, 2019

A research team has found a compound that works to promote rebuilding of the protective sheath around nerve cells that is damaged in conditions such as multiple sclerosis.

Myelin forms a protective sheath covering each nerve cell. Damage to myelin is associated with MS, stroke, brain injuries, and certain forms of dementia such as Alzheimer's disease.

Researchers found that a molecule called hyaluronic acid, or HA, accumulates in the brains of patients with MS. HA then breaks down into small fragments in multiple sclerosis lesions by enzymes called hyaluronidases. Hyaluronidases leads to failure of generation of myelin.

Now researchers have found a modified flavonoid—a class of chemicals found in fruits and vegetables, that can block hyaluronidases and promote remyelination.

The team is preparing for clinical trial, in a year the result will come out if this will work for human being with MS.
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