What Is Treatment of Idiopathic Thrombocytopenic Purpura?

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People with mild idiopathic thrombocytopenic purpura can actually get recovered without treatment. They might only need regular monitoring and platelet checks. If the condition is severe or long-term, treatment will be needed and it may include medications to boost your platelet count or surgery to remove your spleen (splenectomy). Medications that may be prescribed for idiopathic thrombocytopenic purpura include:
  • Drugs that suppress your immune system. They may help raise your platelet count by decreasing the activity of your immune system.Long-term use of these medications isn't recommended because of the risk of serious side effects.
  • Injections to increase your blood count. An injection of immune globulin (IVIG) may be used if you have critical bleeding or need to quickly increase your blood count before surgery.
  • Drugs that boost platelet production. Thrombopoietin receptor agonists such as romiplostim (Nplate) and eltrombopag (Promacta) help your bone marrow produce more platelets.
  • Other immune-suppressing drugs. Rituximab (Rituxan) helps reduce the immune system response that's damaging platelets, thus raising the platelet count.
In some situations, rare and severe bleeding can occur. Emergency treatment usually includes transfusions of platelet concentrates, intravenous corticosteroid (methylprednisolone) and intravenous immune globulin. If your condition persists despite treatment, you might need to get:
  • Removal of your spleen. This quickly eliminates the main source of platelet destruction in your body and improves your platelet count. It's rarely used.
  • Other drugs. Azathioprine (Imuran, Azasan) has been used to treat ITP.
Keywords: idiopathic thrombocytopenic purpura treatment
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