What Is Nephrogenic Systemic Fibrosis?

1 Answer

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Nephrogenic systemic fibrosis can lead to fibrosis of the skin and internal organs. If one gets nephrogenic systemic fibrosis, a large area of his skin will become thick and dark. The symptom is similar to some skin diseases, such as scleroderma or scleromyxedema, but they are different. Besides, the disease may also affect the lungs, the heart and kidneys. Nephrogenic systemic fibrosis results from exposing to gadolinium used in imaging studies in patients with kidney failure. So, the disease often occurs in people with advanced kidney failure. Keywords: nephrogenic systemic fibrosis
What's the treatment for systemic fibrosis
1. Physical therapy. Physical therapy that helps stretch the involved limbs may help slow the progression of joint contractures and preserve movement.

2. Kidney transplant. For people who are appropriate candidates, improvement in renal function because of a kidney transplant may help improve nephrogenic systemic fibrosis over time.

3. Ultraviolet A phototherapy. Exposure of the skin to ultraviolet A light may reduce the skin thickening and hardening, but it's unclear if the treatment penetrates deeply enough into the skin to be effective.

4. Extracorporeal photopheresis. This treatment involves drawing the blood outside the body and treating the blood with a drug that sensitizes it to ultraviolet light. The blood is then exposed to ultraviolet light and returned to the body. Some people have shown improvement after receiving this therapy.
My husband is on dialysis. His legs are hard and thick, and he walks with a stiff gate. What can we  do?
It could probably be caused by the mineral bone disease that is prevalent in patients with dialysis. Briefly, dialysis makes bones deformed and rigid, brittle. You can talk to a nephrologist to comprehensively evaluate his bone status.
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