What is the definition of non-hodgkin lymphoma?
is a cancer that originates in the cells of the lymphatic and immune systems
, such as the blood cells known as lymphocytes and the lymph node tissues
Similar to other types of lymphoma, non-hodgkin lymphoma also triggers symptoms
like enlarged lymph nodes, fever, unexplained weight loss, persistent fatigue or tiredness, night sweats
and so on.
It can also be diagnosed through bone marrow biopsy, blood tests, positron emission tomography (PET)
, and magnetic resonance imaging (MRI)
What causes non-hodgkin lymphoma?
The causes of lymphoma vary from type to type, the following introduce several possible causes of non-hodgkin lymphoma:
- Chemicals: like diphenylhydantoin, dioxin, polychlorinated biphenyls, and phenoxy herbicides.
- Autoimmune diseases: like rheumatoid arthritis, systemic lupus erythematosus, celiac disease, and Sjögren's syndrome.
- Medical treatments: like radiation therapy and chemotherapy.
- Exposure to infectious agents: like Epstein-Barr virus, human T-cell leukemia virus, helicobacter pylori, HHV-8, HIV virus, and hepatitis C virus.
- Genetic diseases: like ataxia telangiectasia syndrome, Klinefelter's syndrome, and Chédiak-Higashi syndrome.
What is the life expectancy or prognosis of non-hodgkin lymphoma?
Affected by numbers of different risk factors, the prognosis or life expectancy of patients with non-hodgkin lymphoma is complicated
It is reported that the overall five-year survival rate is 69%
, and ten-year survival rate is 58%
What are the treatments for non-hodgkin lymphoma?
Depending on different types, stages, and symptoms of the non-hodgkin lymphoma, common treatments
for non-hodgkin lymphoma include:
- Tyrosine kinase inhibitors
- Immunotherapy, including monoclonal antibodies.
- Radiation therapy
- Stem cell transplant
- Other surgeries
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