Glioblastoma Brain Tumor

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What is glioblastoma brain tumor? Glioblastoma, also known as glioblastoma multiforme, is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma can occur at any age, but tends to occur more often in older adults. What are the symptoms of glioblastoma brain tumor? The symptoms of glioblastoma brain tumor can be:
  • headaches
  • nausea
  • vomiting
  • seizures
  • changes to personality,mood or concentration
What are the treatments of glioblastoma brain tumor?
  • Surgery to remove the glioblastoma
  • Radiation therapy
  • Chemotherapy
  • Tumor treating fields (TTF) therapy
  • Targeted drug therapy
  • Clinical trials
  • Supportive (palliative) care
  Keywords: glioblastoma brain tumor, brain tumor glioblastoma, gbm brain tumor, glioblastoma brain tumor, glioblastoma brain tumors, glioma brain tumor, glioma brain tumors
Glioblastoma (GBM) is one of the most aggressive forms of human brain cancer, which kills thousands of patients within a year. Tumor cells develop resistance to the treatments, making them ineffective.

Aug 5, 2019, scientists from Brain Tumor Research Center of University of Portsmouth showed a combination of three regular ingredients, called P1867B, worked with existing cancer treatments boosting their effectiveness and, in some cases, restored sensitivity to some treatments.

In a mice model,  P1867B worked to reduce the size of Glioblastoma. P1867B is a combination of aspirin, triacetin and saccharin, all of which are common.

The next step is to run the first trial i n humen.
What are expected outcome?
Hi, a standard process of new drug development include mouse model trial, clinical trial phase I,II and III. When everything goes as expected, after phase III the new drug will get FDA approval, shrink the tumor size and extend life.

Expected outcome is the drug works effective in human.
Sep 10, 2019

A research team from the University of Georgia's Regenerative Bioscience Center has found that a compound molecule Surfen could be used to treat glioblastoma, an aggressive, usually fatal form of brain cancer.               

Surfen, a compound molecule first described in 1938, is a pharmaceutical agent used to optimize insulin delivery. The UGA researchers identified that surfen-treated cells were "blocked" from tumor growth, and the spread of tumor cells in the brain.          

Surfen doesn't kill the tumor cells but blocks its prey, the tumor may still grow, but at least now it doesn't have any invasive inroads to creep into other parts of the brain.
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