An elevated level of GGT could be the result of liver diseases such as scarring, necrosis, tumors, ischemia or hepatitis.
Other medical conditions that could cause it include pancreatitis, diabetes or heart failure. Lung disease and the blockage of bile from the liver are other potential causes. The use of drugs that are toxic to the liver or alcohol abuse may also increase GGT levels.
An elevated level of gamma-glutamyl transpeptidase enzymes indicates that there is liver damage, but the GGT test does not determine the cause. Some symptoms of high GGT include fatigue, decreased appetite, nausea, vomiting, and swelling or pain in the abdomen.
Generally, the higher the level of GGT, the more damage has been done to the liver. This could rule out bone disease as the cause if the level of alkaline phosphatase enzymes in the liver is also high. Other symptoms of elevated GGT include light-colored stools, dark-colored urine, jaundice and itching.
Keywords: GGT level; liver disease; lung disease