What do Alpha Blockers do in Treating Pheochromocytoma?

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For individuals with pheochromocytoma, Surgery may be the definitive treatment. But before the operation, the patient must be given alpha- and beta blockers (blocking agents). Both blockers function in controlling blood pressure and preventing a hypertensive crisis during the surgery. Alpha blockers are particularly required while beta blockers are used if significant tachycardia, abnormal rapid heart beating, occurs after alpha blockade. And beta blockers are not administered until adequate alpha blockade has been established. Examples of alpha blockers
  • Doxazosin (Cardura)
  • Prazosin (Minipress)
  • Terazosin
Side effects and cautions Some alpha blockers might have a "first-dose effect." It means when you start taking an alpha blocker, you might develop pronounced low blood pressure and dizziness. Therefore, the first dose is often taken at bedtime. Other side effects might include: • Headache • Pounding heartbeat • Weakness • Dizziness • Weight gain WARNING: As alpha blockers may influence the effects of other medications you take, be sure your doctor knows what other medications you take before taking it. Keyword: alpha blockers pheochromocytoma