What Is Marantic Endocarditis?

1 Answer

Q: What is marantic endocarditis? A: Marantic endocarditis, also known as nonbacterial thrombotic endocarditis, is associated with cancer and other debilitating diseases. According to Wikipedia, it is a form of endocarditis in which small sterile vegetations are deposited on the valve leaflets. Marantic vegetations are often associated with previous rheumatic fever. Other risk factors include:
  •  hypercoagulable states
  • malignant cancers, especially mucin-producing adenocarcinomas (most commonly associated with pancreatic adenocarcinomas)
  • systemic lupus erythematosus: referred to as Libman-Sacks endocarditis
  • trauma (e.g., catheters)
The disease affects the valves with the following predilection: mitral valve > aortic valve > tricuspid valve > pulmonary valve.   Keyword: marantic endocarditis.  
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