What Is Amyopathic Dermatomyositis?

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Amyopathic dermatomyositis is a rare, idiopathic, connective tissue disease that presents with dermatologic lesions of classic dermatomyositis but lacks the myopathy of this disease. Cutaneous manifestations may include Gottron’s sign, heliotrope rash, and characteristic patterns of poikiloderma. Amyopathic dermatomyositis accounts for 5-20% in dermatomyositis, with an average onset age of 51.2 years and the ratio of male to female of 1:1.6. Patients with amyopathic dermatomyositis are likely to develop interstitial lung disease or malignancy.   Keywords: amyopathic dermatomyositis; amyotrophic dermatomyositis.