What Is Juvenile dermatomyositis?

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Juvenile dermatomyositis (JDM), also called pediatric dermatomyositis, is a childhood disease which affects the skin (dermato) and muscles (myositis), as well as other parts of the body including joints, lungs, gut and blood vessels.   JDM is an immune-mediated multisystem disease characterized by acute or chronic non-suppurative inflammation of the striated muscle and skin, with early stages of occlusive vascular disease and advanced calcification.   About 10% of patients have other connective tissue diseases, such as JIA, SLE, scleroderma, etc., and a small number of malignant tumors. In severe cases, symptoms are mainly respiratory failure and gastrointestinal ulcers and bleeding.   Keywords: juvenile dermatomyositis; juvenile dermatomyositis children; pediatric dermatomyositis