What Is the Life Expectancy of Progeria Patients?

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Q: What is the life expectancy of progeria patients? A: Death occurs as a result of complications of severe atherosclerosis, either cardiac disease (myocardial infarction) or cerebrovascular disease (stroke), generally between ages of six and twenty. Average life expectancy is approximately 14.6 years. In children with progeria, genetic factors increase the risk of developing progressive heart disease from an early age. According to reports in the medical literature, individuals with progeria develop premature, widespread thickening and loss of elasticity of artery walls (arteriosclerosis), which result in life-threatening complications during childhood, adolescence, or early adulthood. As with any person suffering from heart disease, the common problems as heart disease advances for children with progeria can include high blood pressure, strokes, angina (chest pain due to poor blood flow to the heart itself), enlarged heart,and heart failure. Understanding progeria appeals to scientists. It may offer new insights into the aging process. In 2014, another study indicated that an FTI (Farnesyltransferase inhibitors) known as lonafarnib may increase lifespan by an average of 1.6 years.   Keywords: life expectancy progeria; life progeria; life span progeria; progeria life expectancy; progeria life span.