What Is Lupus Panniculitis?

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Lupus panniculitis, also known as lupus profundus (LP), is a usual manifestation of lupus erythematosus characterized by red, firm, noticeable nodules and plaques on the skin. The disorder usually occurs in adults aged 20 to 60. Risk Factors The exact cause of lupus panniculitis is still not well-understood. But there are some risk factors for the disease.
  • About 33% patients with longstanding cutaneous lupus erythematosus are observed with lupus panniculitis;
  • About 2-5% of the cases are associated with systemic lupus erythematosus (SLE).
Diagnosis It is hard to diagnose lupus panniculitis in early stage since its symptoms may be confused with other septal patterns of panniculitis. Usually it is detected and diagnosed by both clinical and histologic findings. Treatments If you are diagnosed with the disease, your doctor may suggest that you should use following medications, such as:
  • topical glucocorticosteroids and lubricant ointments;
  • antimalarial drugs;
  • Thalidomide, if you do not respond to other methods of therapy.
If you have any questions you don’t understand, please go to see a doctor for professional help. Key words: Lupus panniculitis; Lupus profundus (LP); lupus erythematosus; systemic lupus erythematosus (SLE).
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