What is Lupus Anticoagulant Testing?

1 Answer

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Q: What is lupus anticoagulant testing? A: Lupus anticoagulant (LA) testing is a series of tests used to detect lupus anticoagulant in the blood. Why get tested:
  • help investigate the cause of a blood clot (thrombotic episode)
  • evaluate a prolonged partial thromboplastin time (PTT)
  • help determine the cause of recurrent miscarriages, or as part of an evaluation for antiphospholipid syndrome
When to get tested:
  • have signs and symptoms of a blood clot in a vein or artery
  • have a prolonged PTT test
  • have recurrent miscarriages
If the lupus anticoagulant is present according to the testing result, you need to repeat the testing about 12 weeks later in order to confirm that LA still exists, especially for those who are tested for antiphospholipid syndrome The following tests may be done to help diagnose a lupus anticoagulant:
  • Coagulation factor assays: rule out factor deficiencies that may cause a prolonged PTT and bleeding episodes; also help in detecting lupus anticoagulant.
  • Complete blood count (CBC): includes a platelet count; mild to moderate thrombocytopenia (low platelet count) is often seen along with the lupus anticoagulant; moderate to severe thrombocytopenia may develop in patients receiving anticoagulant (heparin) therapy for lupus anticoagulant-associated thrombosis.
  • Tissue thromboplastin inhibition test (rarely performed nowadays)
If you have any questions, please consult your doctor. Keywords: lupus anticoagulant testing
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