CIDP, chronic inflammatory demyelinating polyneuropathy, is an acquired immune-mediated inflammatory disorder
of the peripheral nerves
characterized by gradually increasing sensory loss
associated with loss of reflexes
CIDP results from damage to the myelin
, covering of the nerves. It can occur at any age
and is more frequent in men than women.
If untreated, 30% of CIDP patients will progress to wheelchair dependence. And early diagnosis and proper treatments can avoid disability in a significant extent.
According to some studies, the progressive category
of CIDP is more common than relapsing-remitting one
are more likely to be all affected than the individual.
that are not significantly associated with prognosis
- course of disease
- sensory disturbance
- muscle strength
- tendon reflexes diminish
- autonomic nervous symptoms
- muscle atrophy
- cerebrospinal fluid protein content
The risk factor
for CIDP is axonal involvement
, and the protective factor
is immunoglobulin therapy
The prognosis of axonal involvement group is worse than the simple demyelinating group.
Keyword: prognosis of cidp patients.