What Is the Prognosis of CIDP patients?

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CIDP, chronic inflammatory demyelinating polyneuropathy, is an acquired immune-mediated inflammatory disorder of the peripheral nerves characterized by gradually increasing sensory loss and weakness associated with loss of reflexes. CIDP results from damage to the myelin, covering of the nerves. It can occur at any age and is more frequent in men than women. If untreated, 30% of CIDP patients will progress to wheelchair dependence. And early diagnosis and proper treatments can avoid disability in a significant extent. According to some studies, the progressive category of CIDP is more common than relapsing-remitting one, myelin and axon are more likely to be all affected than the individual. Moreover, factors that are not significantly associated with prognosis include:
  • age
  • course of disease
  • sensory disturbance
  • muscle strength
  • tendon reflexes diminish
  • autonomic nervous symptoms
  • muscle atrophy
  • cerebrospinal fluid protein content
The risk factor for CIDP is axonal involvement, and the protective factor is immunoglobulin therapy. The prognosis of axonal involvement group is worse than the simple demyelinating group. Keyword: prognosis of cidp patients.