What’s Pathology of Hypertensive Heart Disease?

1 Answer

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  • Systemic Hypertension:
Hypertension occurs when the persistent systolic pressure is greater than 140 and diastolic pressure, more than 90 mm Hg. The major causes of systemic hypertension:
  1. Renal:
  2. a) Vascular disease
  3. b) Parenchymal renal disease
  4. c) Perinephric disease
  5. Cerebral:
  6. a) Increased intracranial pressure
  7. b) Anxiety states
  8. c) Lesions of brainstem
  9. Cardiovascular: Coarction of aorta
  10. Endocrine:
  11. a) Pheochromocytoma
  12. b) Adrenocortical adenomas
  13. c) Pituitary adenomas
  1. Preeclampsia and eclampsia.
  2. Unknown causes
  • Systemic Hypertensive Heart Disease:
Hypertensive heart disease is a typical form of heart disease. 1)Features: - Patient once had hypertension. -LVH, concentric type. -No other lesions that might cause cardiac hypertrophy. Eg: Aortic valve stenosis. 2) Pathogenesis: -There is myocytic hypertrophy as aresult of the increased work. -Thickened myocardium reduces left ventricle compliance, destroying diastolic filling. -Individual myocyte hypertrophy raises the distance for oxygen and nutrient diffusion from adjacent capillaries. -In many patients there is associated coronary atherosclerosis accompanying hypertension which may further lead to ischemia. 3) Fate: -Patients die from congestive heart failure; -Complications of coronary artery disease, such as myocardial infarction may take pace; -There is added risk of sudden death; -Some patients die from renal disease, stroke etc. ; -Fibrinous pericarditis may be obvious in patients who die from uraemia  ; -Therapeutic control of pressure may cause regression of the enlarged myocytes and reduction of heart size.   Keywords: pathology hypertensive heart disease; pathophysiology hypertensive heart disease.   Related FAQ: http://healthtopquestions.com/?p=5058 http://healthtopquestions.com/?p=5044 http://healthtopquestions.com/?p=5038