What is pineal parenchymal tumor of intermediate?

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Pineal parenchymal tumor (PPT) of intermediate is a rare type of tumors of the central nervous system. It was first classified by World Health Organization (WHO) in 2000 because it's hard to find by researchers.

Histopathologically, they are a very heterogeneous group of tumors. These tumors usually affect young people under 20 years old.

Patients usually suffer from:

  • chronic headaches
  • diplopia
  • gait disturbances

Doctors diagnose it based upon biopsy, which is very troublesome. 

Although there are no optimal treatments, most patients are treated with surgical resections. Radiotherapy is also used in the treatment. Besides, radiation and chemotherapy have been reported to be effective for the prevention of the local tumor dissemination.

However, most cases of PPT are not completely removed due to its location.