Complications of Hunter Syndrome

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As Hunter syndrome develops, a variety of complications can occur depending on the type and severity of the disease. To put it simply, it may affect many organs and parts of body such as the lungs, heart, joints, connective tissue, and brain and nerve system.


Thickening of heart tissue can cause improper closing of heart valves, leading to the lack of blood in the heart and other parts of the body.

2.joints and connective tissue

It may cause your joint connective tissues to swell and accumulate undigested complex sugar molecules. As it progresses, you may feel joint stiffness and you will likely move less.

3.Brain and nerve system

Many neurological problems are caused by buildup of excess fluids in your child’s brain. Pressure from these fluids can cause other problems that may cause severe headaches, interfere with vision and change your child’s mental state.
Hunter Syndrome can cause an enlarged tongue, thickened gum, and thickening of the nasal passages and windpipe, which in result will make breathing difficult.

Sorry that I’ve left this part out.
I’ve got a question here. Will girls be affected by this syndrome?
Usually, it is more common among boys. Girls are far less at risk of developing this disease because they inherit two X chromosomes.
Hunter syndrome nearly always occurs in males. Girls are far less at risk of developing this disease because they inherit two X chromosomes.
What kind symptoms are presented if affected?
Symptoms vary from case to case depending on the severity of the syndrome. They are not presented at birth, but usually begin around ages 2-4. In most cases, children may have the following symptoms: joint stiffness, aggressive behavior, stunted growth, a deep, hoarse voice, an enlarged head, a protruding tongue, thickening of the lips, a broad nose and flared nostrils, chronic diarrhea, abnormal bone size or shape and other skeletal irregularities, white skin growths that resemble pebbles, a distended abdomen, and late walking or talking.